Lectins are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes,including embryogenesis,inflammatory responses,cell progression and metastasis. Galectin-3 can function intracellularly in controlling cell cycle and preventing T-cell apoptosis,and also extracellularly,in activating various cells,including monocytes/macrophages,mast cells,neutrophils,and lymphocytes. Human Galectin-3 is a globular 26.0 kDa protein containing 250 amino acid residues.