LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes，activated PBL，CD8+ tumor infiltrating lymphocytes，granulocytes and monocytes. LIGHT has the ability to activate NFkB，stimulate proliferation of lymphocytes，and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors； the herpes virus entry mediator type A receptor （HEVM），LTbR and a decoy receptor （DcR3）.
应用类型
Western blotting （0.5-1 ug/ml）. However， the optimal conditions should be determined individually. The antibody detects human LIGHT. Reactivity to other species has not been tested.
免疫原
Recombinant human LIGHT
来源宿主
兔
反应性
经检测验证，可与人种属来源的LIGHT蛋白发生免疫反应.
保存建议
提供的LIGHT抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油， 1% BSA， 0.02%硫柳汞的PBS （pH 7.2）缓冲液中.请将该LIGHT抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
