TGF-B(transforming growth factor-beta) is a family of multifunctional proteins. TGF-B was originally identified for its ability to induce the growth of normal rodent fibroblast in soft agar. It is now known that TGF-B is a potent growth inhibitor of many normal and transformed cell lines. It regulates normal cell growth,development and tissue remodeling following injury. TGF-B is produced as latent high molecular weight complexes. The activation of latent TGF-B is an important step in the regulation of its action.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 374 of human TGF-B1.