TGF-B (transforming growth factor-beta) is a family of multifunctional proteins. TGF-B was originally identified for its ability to induce the growth of normal rodent fibroblast in soft agar. It is now known that TGF-B is a potent growth inhibitor of many normal and transformed cell lines. It regulates normal cell growth,development and tissue remodeling following injury. TGF-B is produced as latent high molecular weight complexes. The activation of latent TGF-B is an important step in the regulation of its action.
应用类型
Western blot analysis (0.5-4 ug/ml) and Immunohistochemistry (10-20 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Recombinant TGF-B1
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠、猪种属来源的TGF-beta1蛋白发生免疫反应.
保存建议
提供的TGF-beta1抗体产品为100 ug 无色溶液,其浓度为0.2 mg/ml,溶解于包含有50%甘油, 1% BSA, 0.02%硫柳汞的PBS (pH 7.2)缓冲液中.请将该TGF-beta1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.