SLC (secondary lymphoid-tissue chemokine,also called 6Ckine,TCA4,Exodus-2) is a 111-amino acid (human; 110 a.a. for mouse) CC chemokine with an N-terminal sequence of 23 residues as a signal sequence. It was originally cloned in 1997. Recombinant SLC attracts T-,B- cells,mature dendritic cells,but did not induce any cell migration in neutrophils or monocytes. SLC is a functional ligand for CCR7.
应用类型
Western blot analysis (0.5-1 ug/ml). However, the optimal conditions should be determined individually. Cross-reactivity to SLC of other species has not been determined.