WD repeat domain 18 （WDR18） is a member of the WD repeat protein family，which is involved in a variety of cellular processes，including cell cycle progression，signal transduction，apoptosis，and gene regulation. WD repeats are minimally conserved regions of approximately 40 amino acids that commonly form a tertiary propeller structure. WDR18 is a 432 amino acid protein that contains six WD repeats and is encoded by a gene located on human chromosome 19. WDR18 may play a role during development. The complex PELP1-TEX10-WDR18 is required for the maturation and nucleolar release of the large ribosomal subunit .
应用类型
Western Blot: 1 ug/ml， IHC: 2.5 ug/ml， ELISA. However， the optimal conditions should be determined individually.
免疫原
WDR18 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human WDR18.
