SDF-1B （stromal cell-derived factor-B），also known as pre-B-cell growth-stimulating factor （PBSF），is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis. SDF-1 has been shown to be chemotactic for lymphocytes. In addition，SDF-1 was recently reported to be a ligand for CXCR4 （LESTR/fusin），a co-receptor for HIV-1 entry into T cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry.
应用类型
Western blot analysis （0.5-4 ug/ml）. Per researcher’s feedback， the antibody can be used in immunoprecipitation （4-8 ug/ml） and Immunohistochemistry （10-20 ug/ml）. However， the optimal conditions should be determined individually. Cross-reactivity to SDF-1B of other species has not been determined.
免疫原
E. coli-expressed mouse SDF-1B
来源宿主
兔
反应性
经检测验证，可与小鼠、大鼠种属来源的SDF-1beta蛋白发生免疫反应.
保存建议
提供的SDF-1beta抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该SDF-1beta抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
