PTPRD （Protein tyrosine phosphatase receptor type D） is a member of the protein tyrosine phosphatase （PTP） family that plays diverse roles during development including cell growth，differentiation，mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region，a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains. PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiform （GBMs） and multiple human cancers.
应用类型
Western Blot: 1 - 2 ug/ml， ELISA. However， the optimal conditions should be determined individually.
免疫原
PTPRD antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PTPRD.
