The Delta-like 1 homolog （DLK1） is a transmembrane protein containing six epidermal growth factor repeats. It is involved in the differentiation of several cell types，including adipocytes and is also thought to be a tumor suppressor. The DLK1 gene is one of several imprinted genes located in a region on chromosome 14q32； certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 （UPD14）. DLK1 is expressed from the paternal allele； a polymorphism within this gene has been associated with child and adolescent obesity.
应用类型
Western Blot: 1 - 2 ug/ml， ELISA. However， the optimal conditions should be determined individually.
免疫原
DLK1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DLK1.
