KC,a homolog of human and hamster gro/MGSA,is a 72-amino acid CXC chemokine originally cloned from rat macrophages and lung tissue. It is the mediator for recruitment and activation of neutrophils in rat lung inflammation models. Expression of KC can be upregulated by LPS and IL-1-gamma stimulation. IFN-g blocks LPS-induced expression of KC.
应用类型
Western blot, Immunohistochemistry
免疫原
Synthetic peptide surrounding amino acid 78 of mouse KC