Recently，a function has been assigned to a previously identified orphan chemokine receptor，GPR-2. This receptor，also called CCR10，binds with monocyte chemoattractant protein （MCP）-1，MCP-3 and MIP-1 beta. CCR10 is expressed by melanocytes，dermal fibroblasts，dermal microvascular endothelial cells，T cells as well as in skin-derived Langerhans cells. CCR10 may play a role in both skin homeostasis as well as a potential role in inflammatory responses.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The anti-CCR10 antibody recognizes 50 kDa human CCR10 in Western blot analysis.
免疫原
Synthetic peptide surrounding amino acid 353 of human CCR10
来源宿主
兔
反应性
经检测验证，可与人、小鼠种属来源的CCR10蛋白发生免疫反应.
保存建议
提供的CCR10抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该CCR10抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
