IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells，which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper （CD4+） cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally，IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages，NK cells，and neutrophils. Murine IFN-gamma is a 15.6 kDa protein containing 134 amino acid residues.
应用类型
Western blot analysis （0.5-1 ug/ml） and neutralization （0.2-1 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
E. coli expressed murine IFN-gamma
来源宿主
兔
反应性
经检测验证，可与小鼠种属来源的IFN gamma蛋白发生免疫反应.
保存建议
提供的IFN gamma抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有50%甘油和0.02%硫柳汞的PBS （pH 7.2）缓冲液中.请将该IFN gamma抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
