Fractalkine，also known as neurotactin，is a membrane-bound CX3C Chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids，a mucin stalk of 241 amino acids，a putative transmembrane domain of 18 amino acids，and an intracellular tail of 37 amino acids. Within the chemokine domain，the first two cysteine residues are separated by 3 amino acids （CX3C）. Fractalkine message is found in high abundance in the brain，kidney，lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells and may play a role in brain inflammation.
应用类型
Western blot analysis （0.5-4 ug/ml）. Per researcher’s feedback， it can also be used in immunoprecipitation （4-8 ug/ml）， and Immunohistochemistry （10-20 ug/ml）. However， the optimal conditions should be determined individually.
免疫原
E. coli-expressed recombinant human Fractalkine
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Fractalkine蛋白发生免疫反应.
保存建议
提供的Fractalkine抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Fractalkine抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
