Increasing evidence suggests a central role for the CD40L-CD40 signaling pathway in several immunogenic and inflammatory processes，including atherosclerosis. It was also found that CD40L-CD40 signaling pathways play an important role in several autoimmune diseases，including the X-linked hyper-IgM syndrome，collagen-induced arthritis，allergic encephalitis and multiple sclerosis，and acute and chronic graft vs. host diseases.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Recombinant murine CD40L （Cat.# 4015-10） can be used as a positive control.
免疫原
Recombinant murine CD40L
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的CD40L蛋白发生免疫反应.
保存建议
提供的CD40L抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该CD40L抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
