Myeloperoxidase (MPO) is highly expressed in neutrophils and polymorphonuclear luekocytes. MPO is expressed as a dimer in regular neutrophils with a 140 kDA. The glycosylated form of MPO has a molecular weight of 92 kDa and when undergoes a final glycosylation,MPO forms subunits of 60 kDa and 12 kDa. In recent studies,MPO was shown to be involved in the initiation and progression of cardiovascular disease.
应用类型
Myeloperoxidase Sandwich ELISA (Cat # 5012-100 as capture and Cat # 5013-100 as tracer antibody). This pair is able to detect MPO at < 3 ng/ml.