中文名称

【PEDF】再生人色素上皮衍生因子（20 ug）

英文名字

PEDF, human recombinant

供应商

Biovision

产品货号

4988-20

产品报价

￥已停产

产品说明书

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产品新闻

背景资料

PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. PEDF is a 50,000 dalton glycoprotein created and secreted in many tissues all the way through the body. A key component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. Additionally, PEDF is capable to inhibit the activity of angiogenic factors such as VEGF and FGF-2. The recognition of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. The unique range of PEDF activities associate it as a potential therapeutic agent for the treatment of vasculature related neurodegenerative diseases such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF in addition has the potential to be functional in the treatment of various angiogenesis-related diseases including a number of cancers. Recombinant human PEDF produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 400 amino acids and having a molecular mass of 44.5 kDa.

序列

重组人色素上皮衍生因子蛋白产品，又称Pigment epithelium-derived factor, PEDF, Serpin-F1, SerpinF1, EPC-1, EPC1, PIG35.其对应NCBI基因号为5154，NCBI基因别称为PDGFA；该基因种属来源为人源，对应Accession号为P04085.该蛋白产品又称Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1, 等.

来源宿主

提供的【PEDF】重组人色素上皮衍生因子产品的来源为大肠杆菌中重组表达.

溶解建议

提供的重组人色素上皮衍生因子 产品为冻干粉末建议将其重新溶解于无菌纯水至浓度为0.1 -1 mg/ml，使其充分溶解，后继实验可根据实验要求使用合适的水溶液进一步稀释.

保存建议

在您收到艾美捷发出的【PEDF】重组人色素上皮衍生因子产品后，建议将其置于-20°C保存.

其他

BioVision的公司总部在美丽的旧金山湾地区，它是全球生命科学公司的Leader，BioVision在开发和研究细胞凋亡检测分析、代谢检测方面具有卓越的影响力.包括检测各种检测分析试剂盒、相关特色抗体、重组蛋白及细胞因子和酶等多种产品，以及其他创新的研究工具.其产品覆盖细胞凋亡研究、能量代谢、细胞/组织蛋白提取、氧化应激与损伤、代谢与肥胖症、细胞增殖与毒性、信号转导、干细胞研究等领域.作为多家知名品牌的中国总代理以及中国区域代理，艾美捷与BioVision一起为研究者们提供优质、新的细胞生物学研究工具而不断扩大产品及服务质量.

注意

该页面的中文产品信息的翻译，仅供参考。准确的产品信息请以厂家的英文说明书为准。下单前，请浏览说明书确认。

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