The C-terminal glycine carboxyl of Ubiquitin is synthetically modified to an aldehyde. Ubiquitin Aldehyde (Ub-H) is useful in the stabilization of ubiquitin-protein conjugates in vitro, enhancing their accumulation in cell lysates and tissue extracts. Inhibition of deubiquitinylating enzyme activity by Ub-H can be used to identify and confirm such activity and to determine the inhibition kinetics for a particular enzyme. Recommended concentration for maximal inhibition is 2-5 uM. Co-crystallization of ubiquitin aldehyde with specific deubiquitinylating enzymes (the inhibitor mimics the natural ubiquitin substrate) has also been used to probe enzyme:substrate interactions.
重组人泛素醛产品为液体即用型，其溶液组成为：An aqueous solution containing 0.15 M HCl
保存建议
在您收到艾美捷发出的【Ubiquitin Aldehyde】重组人泛素醛产品后，建议将其置于-80°C. Do not lyophilize. Do not neutralize until immediately prior to use. Avoid presence of amino containing compounds.保存.
