IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues.
序列
重组鼠源干扰素-gamma蛋白产品，又称Immune Interferon-γ, type II interferon, T cell interferon, MAF.其对应NCBI基因号为15978，对应Accession号为P01580.
来源宿主
提供的【IFN gamma】重组鼠源干扰素-gamma产品的来源为大肠杆菌重组表达.
溶解建议
重组鼠源干扰素-gamma产品请按照说明书建议进行溶解操作：Reconstitute in ddH₂O to a concentration of 1 mg/ml. Further dilutions should be made into RPMI + 10% FCS and stored at 4°C for 1 week or –20°C for future use. .
