The matrix metalloproteinases （MMP） are a family of peptidase enzymes responsible for the degradation of extracellular matrix components，including collagen，gelatin，fibronectin，laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester，lipopolysaccharide （LPS） or staphylococcal enterotoxin B （SEB）. MMP catalysis requires both calcium and zinc. MMP-9 has been shown to degrade bone collagens in concert with MMP-1 （also designated interstitial collagenase，fibroblast collagenase or collagenase-1），and cysteine proteases and may play a role in bone osteoclastic resorption.
应用类型
The antibody can be used in Western Blot analysis （1-4 ug/ml）. However， the optimal conditions should be determined individually. Recombinant human MMP-9 （Cat.# 7789-10） can be used as a positive control.
免疫原
E. coli-expressed recombinant human MMP-9
来源宿主
兔
反应性
经检测验证，可与人种属来源的MMP-9蛋白发生免疫反应
保存建议
提供的200 ug MMP-9抗体产品为无色溶液其浓度为0.5mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该MMP-9抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
