The phosphodiesterase type-3 （PDE3） family is comprised of 2 isoforms，PDE3A and PDE3B.nPhosphodiesterases （PDE） are crucial in the regulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5’AMP. PDE3B has two splice variants that are expressed in adipocyte tissue，hepatocyte，kidney，spermatocytes and embryonic neuroepithelium. Both PDE3A and PDE3B are potential targets for the treatment of obesity.
应用类型
The antibody can be used for Western blotting （1–4 ug/ml）.
免疫原
Synthetic peptide surrounding amino acid 948 of mouse PDE3B.
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的PDE3B蛋白发生免疫反应
保存建议
提供的200 ug PDE3B抗体产品为无色溶液其浓度为0.5mg/ml溶解于包含有30%甘油， 0.5% BSA， 5 mM EDTA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该PDE3B抗体产品置于-20 °C冷冻保存，建议分装使用以避免反复冻融.
