Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR)，an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle throμgh its ability to integrate signals from nutrient levels and growth factors
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 1075 of mouse TSC1
