AS160 is a 160 kDa Akt serine/threonine kinase substrate that plays a critical role in regulating insulin-stimulated exocytosis of glucose transporter GLUT4. Increased in insulin treatment stimulate phophorylation of AS160 that regulates GLUT4 translocation via inactivation of the Rab GTPase function.
应用类型
The antibody can be used for Western blotting (1–4 ug/ml).
免疫原
Synthetic peptide surrounding amino acid 186 of human AS160/TBC1.
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的AS160/TBC1蛋白发生免疫反应
保存建议
提供的100 ug AS160/TBC1抗体产品为无色溶液其浓度为0.5mg/ml溶解于包含有30%甘油, 0.5% BSA, 5 mM EDTA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该AS160/TBC1抗体产品置于-20 °C冷冻保存,建议分装使用以避免反复冻融.