Insulin stimulates glucose uptake in the muscles and adipose tissues by activating GLUT4 （Glucose Transporter Type 4）. GLUT 4 is a transmembrane protein that facilitates glucose transport from storage sites to cell surface. Human insulin resistance involves a defect in GLUT4 that leads to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface.
应用类型
Western blot analysis （1-4 ug/ml）. However， the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 403 of mouse GLUT4.
来源宿主
兔
反应性
经检测验证，可与小鼠、大鼠种属来源的GLUT4蛋白发生免疫反应.
保存建议
提供的GLUT4抗体产品为200 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该GLUT4抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
