ALK7 or ACVR1C is a type I receptor for TGFB superfamily of signaling protein. Upon ligand binding,type I receptors phosphorylate cytoplasmic SMAD transcription factors,which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 155 of mouse ALK-7