The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain,which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors.TLR11 is activated by uropathogenic bacteria and may play a role in preventing urogenital infections.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 793 of mouse TLR11