The Toll-like receptor （TLR） family of proteins are characterized by a highly conserved Toll homology （TH） domain，which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors.TLR11 is activated by uropathogenic bacteria and may play a role in preventing urogenital infections.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~70-90 kDa of TLR11 in Jurkat cell lysate. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 793 of mouse TLR11
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的TLR11蛋白发生免疫反应.
保存建议
提供的TLR11抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该TLR11抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
