Comparative Gene Identification-58 (CGI-58) is a causal gene of Dorfman-Chanarin syndrome,a neutral lipid storage disease characterized by the presence of intracellular lipid droplets in tissues. CGI-58 comes from a large family of proteins characterized by an /B hydrolase fold that activates adipose triglyceride lipase thus,may involve in lipid metabolism.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~45 kDa of CGI-58 in 3T3 cell lysate. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 218 of human CGI-58
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的CGI-58蛋白发生免疫反应.
保存建议
提供的CGI-58抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该CGI-58抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.