Dipeptidyl peptidase 10 or DPP10 is a single-pass type II membrane protein that belongs to the S9B family of DPP serine proteases. The conserved serine residue which normally found in the serine proteases family is not present in DPP10. Thus,DPP10 has no detectable proteases activity as the active serine site is replaced by a glycine residue. DPP10 cleaves the terminal dipeptides from cytokines and chemokines and also facilitates the voltage-gated potassium channels. It is expressed mostly in the brain and is a potential target for asthma treatment.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~90-97 kDa DPP10 in samples from human, mouse and rat origins.
免疫原
Synthetic peptide surrounding amino acid 642 of mouse DPP10
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的DPP10蛋白发生免疫反应.
保存建议
提供的DPP10抗体产品为200 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该DPP10抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.