NFkB was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is activated by a wide variety of stimuli such as lipopolysaccharide (LPS),pro-inflammatory cytokines,and viral infection. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 955 of human NFkB105