NFkB was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is activated by a wide variety of stimuli such as lipopolysaccharide （LPS），pro-inflammatory cytokines，and viral infection. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes the 105 kDa NFkB p105 in samples from human， mouse and rat origins. Reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 955 of human NFkB105
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的NFkB p105蛋白发生免疫反应.
保存建议
提供的NFkB p105抗体产品为200 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该NFkB p105抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
