IRF3 is interferon regulatory factor 3,a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta,as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3,a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta,as well as other interferon-induced genes.
应用类型
Western blotting (1:200 – 1:500). However, the optimal concentrations should be determined individually.
免疫原
Synthetic peptide of human IRF3
来源宿主
兔
反应性
经检测验证,可与人种属来源的IRF3 Polyclonal蛋白发生免疫反应.
保存建议
提供的IRF3 Polyclonal抗体产品为100 ul 无色溶液,其浓度为N/A,溶解于包含有30%甘油, 1% BSA和0.02%硫柳汞的PBS缓冲液中.请将该IRF3 Polyclonal抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.