Neuropilin 1 is a type 1 membrane-bound coreceptor to a tyrosine kinase receptor for both Vascular Endothelial Growth Factor and Semaphorin family members. Neuropilin 1 is invovled in axon growth and guidance,cell survival,migration,and invasion.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~100-130 kDa band of Neuropilin 1 in samples from human, mouse and rat, origins. A lower band ~50-70 kDa can also be detected, presumably to be the cleavage fragment of Neuropilin-1. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 816 of mouse Neuropilin 1
来源宿主
兔
反应性
经检测验证,可与小鼠、大鼠种属来源的Neuropilin-1蛋白发生免疫反应.
保存建议
提供的Neuropilin-1抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Neuropilin-1抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.