Trek-1 and Trek-2 belong to the tandem-pore K+ channel family that has two pore-forming domains and four transmembrane segments. Trek-1 is expressed throughout the central nervous system whereas Trek-2 is found mostly in the cerebellum，spleen and testis. Trek-1 is activated by arachidonic acid and polyunsaturated fatty acids.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. The antibody recognizes ~47 kDa Trek 1 of human， mouse， and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 417 of mouse Trek-1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Trek1蛋白发生免疫反应.
保存建议
提供的Trek1抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞nn的PBS （pH 7.2）缓冲液中.请将该Trek1抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
