Syndecans are type I integral membrane proteoglycans that are involved in cell-extracellular matrix adhesion and growth factor binding. Syndecan-1 is a matrix receptor which binds to Collagens，Fibronectin and Thrombospondin. Syndecan-1 and Syndecan-3 interact with MK （midkine），a growth/differentiation factor involved in embryogenesis. Syndecan-2 is highly expressed at areas of high morphogenetic activity，such as epithelial-mesenchymal interfaces and the prechondrogenic and preosteogenic mesenchymal condensations. Syndecan-4 functions cooperatively with integrins in the processes of cell spreading and focal adhesion assembly.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been determined.
免疫原
Synthetic peptide surrounding amino acid 427 of human Syndecan-3
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠、鸡种属来源的Syndecan-3蛋白发生免疫反应.
保存建议
提供的Syndecan-3抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Syndecan-3抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
