MGMT Antibody,O-6-methylguanine-DNA methyltransferase,O-6-methylguanine-DNA-alkyltransferase,Methylguanine DNA methyltransferase,Methylated DNA protein cysteine methyltransferase
MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair protein that response to DNA damage by removing methly or alkyl groups from the O6 position of guanine. MGMT protects normal cells from cytotoxic effects and is important in drug resistance to alkylating agents.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually.
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 8 of rat MGMT
来源宿主
兔
反应性
经检测验证,可与小鼠、大鼠种属来源的MGMT蛋白发生免疫反应.
保存建议
提供的MGMT抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该MGMT抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.