PPAR （Peroxisome proliferator-activated receptor） is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARg is preferentially expressed in adipocyte as well as in vascular smooth muscle cells and macrophage. Besides its role in mediating adipogenesis and lipids metabolism，PPARg also modulates insulin sensitivity，cell proliferation and inflammation. The inhibition of PPARg transcription activity is due to MAP kinase phosphorylation at serine 84 of PPARg.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. The antibody recognizes ~33 kDa band， corresponding to PPARg （isoform CRA-c） in samples from human and mouse origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 262 of human PPARg isoform CRA-c
来源宿主
兔
反应性
经检测验证，可与人、小鼠种属来源的PPAR gamma蛋白发生免疫反应.
保存建议
提供的PPAR gamma抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该PPAR gamma抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
