FOXL2 is a nuclear protein specially expressed in eyelids and in fetal and adult ovarian follicular cells. Defects in FOXL2 are cause of blepharophimosis,ptosis and epicanthus inversus syndrome (BPES). It is an autosomal dominant disorder characterized by eyelid dysplasia,small palpebral fissures,drooping eyelids and a skin fold. It is also associated with female infertility.
应用类型
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the FOXL2 of human, mouse, and rat origins. Rat kidney tissue lysate (Cat.# 2702-100) can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 367of human FOXL2
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的FoxL2蛋白发生免疫反应.
保存建议
提供的FoxL2抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该FoxL2抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.