Histone acetyltransferases （HATs） have been implicated in a number of cellular functions including gene regulation，DNA synthesis，and repair. Histone acetyltransferases and deacetylases are respectively，the enzymes devoted to thr addition and removal of acetyl groups from lysine residues on the Histone N-terminal trails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders，including cancer.
应用类型
Western blotting （2-6 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） can be used as a positive control. The antibody recognizes 220 kDa human HAT-3. A 50 kDa unknown band can also be detected. Reactivity to other species has not been determined.
免疫原
Synthetic peptide containing amino acids near the C-terminus of the human HAT-3
来源宿主
兔
反应性
经检测验证，可与人种属来源的HAT-3蛋白发生免疫反应.
保存建议
提供的HAT-3抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该HAT-3抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
