BIK is a member of Pro-apoptotic Bcl-2 family proteins. Although Bik lacks Bcl-2 homologus region,BH1 and BH2,BIK interacts with Bcl-2 and Bcl-xL. BIK has been shown to induce apoptosis by activating caspase-9.
应用类型
Western blotting (2-6 ug/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate (Cat.# 2401-100), mouse small intestine (Cat.# 2601-100) and rat kidney (Cat.# 2702-100) can be used as positive controls. The antibody detects a ~17 kDa BIK in samples from human, mouse, and rat origins. A ~15 kDa cleavage fragment can also be detected
免疫原
Synthetic peptide mapping to N-terminus of human BIK
来源宿主
兔
反应性
经检测验证,可与人、小鼠、大鼠种属来源的BIK蛋白发生免疫反应.
保存建议
提供的BIK抗体产品为100 ug 无色溶液,其浓度为0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA, 0.01%硫柳汞的PBS (pH 7.2)缓冲液中.请将该BIK抗体产品置于-20 ℃冷冻保存,建议分装使用以避免反复冻融.