Sodium glucose co transporters （SGLTs） are located in the brush-border membrane，but transported out of the cell across the basolateral membranes by a facilitated sugar transporter （GLUT）. At least three members of SGLTs （SGLT 1-3） have been cloned and characterized. SGLTs transport a methyl-D-glucoside （a-MDG），a non-metabolized model substrate，in Na-dependent manner. SGLT-1 does not discriminate a-MDG，glucose，and galactose. SGLT2/3 do not transport D-galactose efficiently.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Other applications have not been determined. The antibody detects 74 kDa SGLT-2 from human， mouse， and rat origins. Reactivity to other species has not been determined. A ~55 kDa and a ~45 kDa bands can also been detected， representing the SGLT-2 cleavage fragments.
免疫原
Synthetic peptide near the N-terminus of mouse SGLT-2
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的SGLT-2蛋白发生免疫反应.
保存建议
提供的SGLT-2抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该SGLT-2抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
