The p21-activated kinase （PAK） family of serine/threonine kinases is engaged in multiple cellular processes，including cytoskeletal recognization，MAPK signaling，apoptotic signaling，control of phagocytes，NADPH oxidase and growth factor-induced neurite outgrowth. Research indicates that phosphorylation of serine 139 of PAK3 which is located in the kinase inhibitory domain，affects the kinase activity.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Other applications have not been tested.
免疫原
Synthetic peptide surrounding amino acid 548 of human PAK3
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的PAK3蛋白发生免疫反应.
保存建议
提供的PAK3抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该PAK3抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
