Dvl1，Dvl2，and Dvl3 are mammalian homologs of Dsh （disheveled） proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins，Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers.
应用类型
Western blotting （0.5-4 ug/ml）. The optimal concentrations should be determined individually. A ~80 kDa band and a smaller ~45 kDa cleavage fragment can be detected.
免疫原
Synthetic peptide surrounding amino acid 583 of mouse Dvl3
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Dvl3蛋白发生免疫反应.
保存建议
提供的Dvl3抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该Dvl3抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
