BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC,possibly throμgh activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.
应用类型
Western blot
免疫原
Synthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1