MST-1 （Mammalian STE20-like kinase 1） is a serine/threonine kinase that has been implicated to play a role in chromatin condensation. Its C-terminal contains nuclear export signals which are released upon caspase mediated cleavage. The N-terminus portion of MST-1 then translocates to the nucleus and will promote chromatin condensation. The full length of MST-1 is localized to the cytoplasm.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） can be used as a positive control. The antibody recognizes MST-1/Krs-2 at 50-60 kDa in samples from human， mouse and rat origins. Reactivity to other species has not been tested.
免疫原
Synthetic peptide surrounding amino acid 13 of Human MST-1
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的MST-1/Krs-2蛋白发生免疫反应.
保存建议
提供的MST-1/Krs-2抗体产品为100 ug 无色溶液，其浓度为0.2 mg/ml，溶解于包含有0.1% BSA， 30%甘油和0.01%硫柳汞的PBS缓冲液中.请将该MST-1/Krs-2抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
