Cyr61 is a member of angiogenic and vasculogenic regulators designated CCN proteins，which includes CTGF，Cyr61 homolog，Fisp2. Cyr61 functions as an angiogenic inducer，stimulating cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Elevated expression of Cyr61 is observed during vessel growth，wound healing and chondrocyte differentiation.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Jurkat cell lysate （Cat.# 2401-100） and mouse small intestine tissue lysate （Cat.# 2601-100） can be used as positive controls. The antibody detects the full length and cleaved form of Cyr61 protein from samples of human， mouse and rat origins. Cross-reactivity to other species has not been determined.
免疫原
Synthetic peptide surrounding amino acid 166 of mouse Cyr61
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的Cyr61蛋白发生免疫反应.
保存建议
提供的Cyr61抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA， 0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该Cyr61抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
