Selectins are a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. E-Selectin （also called ELMA-1） expressed on endothelial cells. L-Selectin （also called LECAM-1） is expressed on the majority of B and naïve T cells and on most monocytes，neurophils and eosinophils. P-Selectin （also called GMP-140） expressed on activated platelets and endothelial cells. Selectins interact with specific carbohydrates expressed by activated endothelial cells，monocytes，and neutrophils.
应用类型
Western blotting （0.5-4 ug/ml）. However， the optimal concentrations should be determined individually. Jurkat cell lysate （Cat.# 2401-100） can be used as a positive control.
免疫原
Synthetic peptide surrounding amino acid 756 of mouse P-Selectin
来源宿主
兔
反应性
经检测验证，可与人、小鼠、大鼠种属来源的P-Selectin蛋白发生免疫反应.
保存建议
提供的P-Selectin抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS缓冲液中.请将该P-Selectin抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.
