Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression,schizophrenia,Parkinson’s disease and drug abuse (Kish et al.,2001; Zhu et al.,2000; Zhu et al.,1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al.,2000; Salvatore et al.,2001; Dunkley et al.,2004).
应用类型
The antibody can be used for Western blotting (1:1000). However, the optimal conditions should be determined individually.
免疫原
SDS-denatured rat tyrosine hydroxylase, purified from pheochromocytoma.
来源宿主
兔
反应性
经检测验证,可与哺乳动物种属来源的Tyrosine Hydroxylase蛋白发生免疫反应
保存建议
提供的100 ul Tyrosine Hydroxylase抗体产品为无色溶液其浓度为N/A溶解于包含有50%甘油, 0.01% BSA、150 mM NaCl和10 mM HEPES缓冲液(pH 7.5)中.请将该Tyrosine Hydroxylase抗体产品置于-20 °C冷冻保存,建议分装使用以避免反复冻融.