HDAC3 is a member of the class I mammalian histone deacetylase family,which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC3 is composed of 428 amino acid residues. HDAC3 interacts with a growing number of transcriptional factors including SMRT and N-CoR. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
应用类型
Western blot, Immunohistochemistry
免疫原
Synthetic peptide corresponding to the C-terminus of human HDAC-3