HDAC1 is an active component of transcriptional corepressor complexes which can be recruited to specific promoter regions via transcriptional factors. HDAC1 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions，which leads to the inhibition of gene transcription.
应用类型
Western blotting, Immunoprecipitation, Immunohistochemistry
免疫原
Synthetic peptide corresponding to the C-terminus of human HDAC1
