Galectins are a family of soluble B-galactoside-binding animal lectins that modulate cell-to-cell and cell-to-ECM interactions,as well as apoptosis. Galectin-3 encodes a 30-35 kDa protein containing a single carbohydrate binding domain,which binds galactose-containing glycoconjμgates. Upregulated expression of Galectin-3 is involved in cancer progression and metastasis.
应用类型
Western blot
免疫原
Synthetic peptide surrounding amino acid 188 of human Galectin-3